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Pefloxacin Mesylate Dihydrate
CAS No. 149676-40-4
Pefloxacin Mesylate Dihydrate( Pefloxacin Mesylate Dihydrate | Pefloxacin (mesylate dihydrate) | Peflacin )
Catalog No. M12077 CAS No. 149676-40-4
Pefloxacin mesylate dehydrate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 47 | In Stock |
|
| 200MG | 65 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePefloxacin Mesylate Dihydrate
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NoteResearch use only, not for human use.
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Brief DescriptionPefloxacin mesylate dehydrate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse).
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DescriptionPefloxacin mesylate dehydrate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse).
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In Vitro——
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In Vivo——
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SynonymsPefloxacin Mesylate Dihydrate | Pefloxacin (mesylate dihydrate) | Peflacin
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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RecptorTopo II
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number149676-40-4
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Formula Weight465.49
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Molecular FormulaC17H20FN3O3·CH4O3S·2H2O
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Purity>98% (HPLC)
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SolubilityWater: 67 mg/mL (143.93 mM); DMSO: 9 mg/mL (19.33 mM)
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SMILESCCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O.CS(=O)(=O)O.O.O
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Chemical Name1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;methanesulfonic acid;dihydrate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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DRF-1042
DRF-1042, an orally active camptothecin analog, exhibits anticancer and insecticidal activities by inhibiting DNA topoisomerase I. It has been studied for its efficacy against solid tumors, including prostate and colon cancers.
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Exatecan Mesylate
Exatecan Mesylate is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL).Exatecan Mesylate (DX-8951f) significantly inhibits the proliferation of several cancer cell lines, with mean GI50s of 2.02 ng/mL, 2.92 ng/mL, 1.53 ng/mL, and 0.877 ng/mL for breast cancer cells, colon cancer cells, stomach cancer cells and lung cancer cells, respectively.
